Antiparasitics Hapten Design and Synthesis
The global use of antiparasitic agents in veterinary medicine and agriculture has raised increasing concerns about drug residues in food products and the environment. Monitoring these residues with high specificity and sensitivity requires the development of robust immunoassay tools, which in turn rely on the availability of high-quality haptens. Creative Biolabs offers comprehensive antiparasitics hapten design and synthesis services, tailored to support the development of competitive ELISAs, lateral flow assays, and other antibody-based detection platforms. Our custom hapten services cover several major classes of antiparasitic drugs, including benzimidazoles, avermectins, and polyether antibiotics.
Benzimidazoles (BZs) Hapten Design & Synthesis
Benzimidazoles are widely used broad-spectrum anthelmintics effective against various parasitic worms. Our team designs and synthesizes functionalized BZ haptens—such as those based on albendazole, fenbendazole, or mebendazole—by modifying reactive sites without disrupting immunodominant structures. These haptens are ideal for generating high-affinity antibodies and constructing accurate assays for trace-level detection in food and biological matrices.
Avermectins (AVMs) Hapten Design & Synthesis
Avermectins, including ivermectin and abamectin, are macrocyclic lactones with potent antiparasitic activity. Due to their complex structures and low immunogenicity, designing effective haptens is technically challenging. At Creative Biolabs, we overcome this by introducing strategic functional groups to retain structural similarity while enabling carrier protein conjugation. Our avermectin haptens support the development of sensitive and specific detection methods compliant with regulatory requirements.
Polyether Antibiotics (PEs) Hapten Design & Synthesis
Polyether antibiotics, such as monensin, narasin, and salinomycin, are ionophoric agents used primarily in poultry and livestock. Detecting their residues requires haptens that closely mimic the polyether scaffold without compromising epitope accessibility. We offer rational design and synthesis of PEs haptens that ensure optimal antibody responses and assay sensitivity, suitable for both screening and quantitative applications.
Why Choose Creative Biolabs' Antiparasitics Services?
At Creative Biolabs, our hapten synthesis services are backed by years of synthetic chemistry expertise, structural biology insights, and immunoassay development experience. We work closely with our clients to customize hapten structures based on their target analytes and intended assay formats. From structure design and linker optimization to carrier conjugation and purity validation, every step is executed under strict quality control.
Our antiparasitics hapten platform ensures:
- Rational hapten design preserving antigenic determinants
- Flexible linker strategies for optimal immunogenicity
- High-purity synthesis and analytical validation
- Application support for immunoassay development
Let Creative Biolabs be your trusted partner in advancing antiparasitic residue detection. Contact us today to learn how our custom hapten design solutions can elevate your research or regulatory testing program.