Full Name: Simvastatin
Synonyms: SVT
Simvastatin is a lipophilic HMG-CoA reductase inhibitor (statin). It is a prodrug hydrolyzed in vivo to its active beta-hydroxy acid, which blocks hepatic cholesterol synthesis and upregulates LDL receptors. It manages hypercholesterolemia and reduces cardiovascular event risks. Its structure contains a hexahydronaphthalene ring linked to a dimethylbutyrate ester and a lactone ring.